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I think it's potentially disastrous, resulting in a variety of effects, including direct spike toxicity, immune exhaustion, tolerance and so on. This paper alone should result in immediate suspension of the products, but none of the previous hundreds of "killer findings" have done that so I suppose this won't either.

But one thing I cannot get my head round is this: for the spike to be made, the cell has to be trasfected. Once transfected, the cells express spike and are marked for destruction by the immune system.

So what is going on? Are cells getting continually transfected (ie that part is happening over time) or are the cells not being destroyed by the immune system? If the latter, why not? I know that the modifications to the mRNA were designed to make it less degradeable, but surely that wouldn't extend as far as protecting the transfected cells from being destroyed, would it?

There seems to be a big piece of the jigsaw missing here...and I don't like the look of what it might represent, as it points towards continued long-term fundamental biological effects of unknown consequence which basically never get switched off in a proportion of those injected.

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I agree Jonathan, this is a disastrous finding!

Maybe another possibility is that the dsDNA plasmids (complete with the SV40 promoter and nuclear localisation signal) are being brought to billions of cell nuclei and are producing spike mRNA which in turn produce ongoing spike protein. If this is widespread, it might overwhelm the capacity of the immune system to deal with it (exhaustion) and the resultant class-switch to IgG4 and tolerance makes sense ... as an attempt to shut down an excessively harmful autoimmune response ... but at what cost? Cancer, increased vulnerability to infection, and more.

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Thanks, JE for being among a brave few who are fighting for humanity.

"....: for the spike to be made, the cell has to be trasfected. Once transfected, the cells express spike and are marked for destruction by the immune system."

From a layman's perspective, that looks like self-destruction! This is beyond perverse. I vaguely understand that the immunity system is to destroy intruders, not their cells!

I agree 100% with the below:

"There seems to be a big piece of the jigsaw missing here...and I don't like the look of what it might represent, as it points towards continued long-term fundamental biological effects of unknown consequence which basically never get switched off in a proportion of those injected."

I also suspect "they" knew what they did, but professed public ignorance. People don't implement detailed, long-term scam without foreknowledge.

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Well tbf the normal immune response does involve destroying the body’s own cells if there’s good reason for it to do so (eg infected by a pathogen). But this is usually quite limited in scope in terms of volume, location and duration.

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Some cells will be recognised and PAMPS will flag them for destruction if they haven't undergone apoptosis already, but spike protein has a trick up its sleeve to be exported from live cells. And synthetic spike mRNA can use the same trick to go everywhere.

Exosomes: potential model for complement-stealth delivery systems

...Despite being effective modulators of immune response, exosomes are not recognized by the immune system as being foreign.

https://www.degruyter.com/document/doi/10.1515/ejnm-2015-0005/html?lang=en

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They knew this back in 2021:

Cutting Edge: Circulating Exosomes with COVID Spike Protein Are Induced by BNT162b2 (Pfizer-BioNTech) Vaccination prior to Development of Antibodies: A Novel Mechanism for Immune Activation by mRNA Vaccines

...Exosomes with spike protein and Abs decreased in parallel after four months.

https://pubmed.ncbi.nlm.nih.gov/34654691/

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They go everywhere

And they linger

Damaging mitochondria

And their precious mtDNA

Dysfunction sets in

Fatigue and irritability follows

Along with sorrows

As they're slowly aging away

Forty years old with eighty year old organs

The stress of living soon overwhelms

And so tired and compliant

Too exhausted to fight

They opt to tap out and obey

So all we can do is pray

That the few who remain on the day

Have a backbone and won't back down and pay

Whatever they're going to charge for the illusion of peace and safety

As society slowly decays away

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It looks and seems very concerning.

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I recently heard Dr David E Martin talk at the 3rd Covid International Summit at the European Union Summit in May 2023. Never ever on Earth has the Human species been subjected to the Warfare being carried out by the Powers that be. Its such a heavy burden to carry the knowledge playing out before our very eyes.

👁💜👁

Why to this very moment the factual evidences presented, has still not yet ended the Big Pharma Global Rollout is the greatest Crime of all?

Where are the Fresh Eyes 👁💜👁

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🇦🇺 “We have just learnt that Senator Katy Gallagher, Finance Minister, is introducing the Digital ID Bill 2023 tomorrow.” ~ Senator Malcolm Roberts, 29 November 2023 (this evening)

https://www.facebook.com/100050536897317/posts/pfbid02wFw2ZF89kJRcxok9BjvcmbLdt8UQnQYcEidb7s33hbErXHEadKJ3MpbNg3usaMhbl/

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