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Deep learning, AI have some predictions about Omicron

Based on a well-tested and experimentally confirmed deep learning model trained with tens of thousands of experimental data, we investigate the impacts of Omicron’s RBD mutations to its infectivity. We show that Omicron is about ten times more infectious than the original virus or about twice as infectious as the Delta variant. Using the structures of 132 known antibody-RBD complexes, we reveal that Omicron’s vaccine-escape capability is about twice as high as that of the Delta variant. We unveil that Omicron may significantly reduce the efficacy of Eli Lilly antibody cocktail. Omicron RBD mutations may also compromise monoclonal antibodies (mAbs) from Celltrion and Rockefeller University.

https://arxiv.org/pdf/2112.01318.pdf